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Epilepsy Research and Treatment
Volume 2013 (2013), Article ID 387510, 4 pages
Review Article

Slowly Evolving Trends in Temporal Lobe Epilepsy Management at London Health Sciences Centre

London Health Sciences Centre, Western University, London, ON, Canada N6A 5A5

Received 19 January 2012; Accepted 15 June 2012

Academic Editor: Seyed M. Mirsattari

Copyright © 2013 Warren T. Blume. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Although the advent of MRI impacted significantly our presurgical investigation, ictal semiology with interictal and ictal EEG has clearly retained its roles in localizing epileptogenesis. MRI-identified lesions considered epileptogenic on semiological and electroencephalographic grounds have increased the likelihood of resective surgery effectiveness whereas a nonlesional MRI would diminish this probability. Ictal propagation and the interplay between its source and destination have emerged as a significant component of seizure evaluation over the past 30 years.