Table of Contents
Epilepsy Research and Treatment
Volume 2013, Article ID 501981, 9 pages
Review Article

Diagnosis and Management of Epileptic Encephalopathies in Children

1Division of Pediatric Neurology, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi 110029, India
2Department of Pediatrics, Lady Hardinge Medical College and Associated Kalawati Saran Children’s Hospital, New Delhi 110001, India
3Department of Neurology, Neurosciences Centre, All India Institute of Medical Sciences, New Delhi 110029, India

Received 13 March 2013; Revised 4 June 2013; Accepted 18 June 2013

Academic Editor: Elaine Wirrell

Copyright © 2013 Puneet Jain et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Epileptic encephalopathies refer to a group of disorders in which the unremitting epileptic activity contributes to severe cognitive and behavioral impairments above and beyond what might be expected from the underlying pathology alone, and these can worsen over time leading to progressive cerebral dysfunction. Several syndromes have been described based on their electroclinical features (age of onset, seizure type, and EEG pattern). This review briefly describes the clinical evaluation and management of commonly encountered epileptic encephalopathies in children.