| | Authors | Sex | Age at AS onset (yrs) | Other seizures | Epilepsy family history | Photo sensitivity | AED therapy | Response of AS to AEDs | Notes |
| | Definite cases of ASE |
| | Nightingale and Welch, 1982 [6] | F | 56 | GTCS | NS | NS | PRI, PHT | Persistence of seizures | |
| | Zambrelli et al., 2006 [7] | M | >20 | GTCS | No | No | LTG, VPA | Seizure free | |
| | Genton et al., 2008 [5] | F | 14 | GTCS | No | No | VPA | Seizure free | | | F | 34 | A | No | No | VPA, LTG | Seizure free | | | F | 16 | GTCS | No | No | VPA, ESM, and CZP | Persistence of seizures | | | M | 35 | GTCS | No | No | VPA, ESM | Seizure free | | | M | 15 | GTCS | No | No | VPA | Seizure free | | | M | 26 | GTCS | No | No | VPA | Seizure free | | | F | 26 | GTCS | No | No | VPA, PB, and LEV | Persistence of seizures | | | F | 65 | GTCS | No | No | VPA | Seizure free | | | M | 16 | A, GTCS | No | No | VPA, LTG | Persistence of seizures | | | M | 36 | A | No | No | LEV, TPM | Seizure free | | | M | 36 | GTCS | No | No | LTG, ESM | Seizure free | |
| | Bilo et al., 2010 [8] | M | 14 | GTCS | No | No | LTG, VPA | Persistence of seizures | |
| | Pro et al., 2011 [9] | F | 54 | No | Yes | Yes | LTG | Seizure free | |
| | Possible cases of ASE (atypical features) |
| | Terzano et al., 1978 [11] | F | 76 | GTCS | No | Yes | ? | ? | Atypical feature: prominent myoclonic jerks during AS |
| | Possible cases of ASE (insufficient data) |
| |
Lee 1985 [12] |
Three patients in this series presented recurring AS, but it is not clear if a defined IGE syndrome and/or other seizures were the main seizure type and/or if AS episodes were situation related. |
| | Berkovic et al., 1989* [13] |
Fourteen patients in this series had recurring AS with onset after the age of 15. An undetermined number of these 14 patients belonged to “the unusual but well-recognized group of IGEs beginning in middle to later life, where AS is a particular prominent seizure type.” |
| | Tomson et al., 1992 [14] |
AS was the only seizure type in 5 patients with undetermined IGE. However, it is not clear whether or not AS was recurring in any of these patients. |
|
Agathonikou et al., 1998 [15]
(patients 18, 19, and 20) | M | 48 | GTCS | NS | NS | VPA, CBZ, and PHT | Seizure free | It is not clear if AS is the main seizure type. | | F | 36 | A, GTCS | NS | NS | VPA | Seizure free | It is not clear if AS is the main seizure type. | | F | 43 | A, GTCS | NS | NS | PB, PHT, ESM, and CZP | Seizure free | It is not clear if AS is the main seizure type. |
|
Szucs et al., 2008 [16]
(patient 2) | F | 45 | GTCS | NS | NS | NS | Seizure free | It is not clear if AS is the main seizure type. |
|
Mireles and O’Donovan, 2010 [17]
(patients 1, 2, and 3) | NS | 49 | A | NS | NS | LEV | Seizure free | Possible diagnosis of CAE | | NS | 60 | GTCS | NS | NS | LEV, LTG, PTH, and VPA | Persistence of seizures | Insufficient clinical data | | NS | 47 | No | NS | NS | VPA | Seizure free | Insufficient clinical data |
| | Possible cases of ASE (prompt diagnosis may have altered natural history) |
|
Iivanainen et al., 1984 [18]
(patient 2) | F | 61 | A, GTCS | No | No | VPA | Seizure free | This patient had few seizures in her life, among which AS does not stand as the main seizure type. However, its low recurrence may be due to prompt diagnosis and treatment. |
| |
Fernández-Torre and Rebollo, 2009 [19] | F | 68 | GTCS | No | Yes | VPA | Seizure free | Concomitant seizures were rare and disappeared after childhood. AS is not recurrent, but this may be due to prompt diagnosis and treatment. |
| | Cases of AS not fulfilling criteria for ASE |
|
Iivanainen et al., 1984 [18]
(patient 1) | F | 55 | A, GTCS | No | No | VPA, PB | | Concomitant seizures were very frequent. |
| |
Michelucci et al., 1996 [20] (patients 1 and 4) | F | 28 | A, GTCS | No | NS | VPA | NS | AS was not the main seizure type. | | M | 41 | A, GTCS | No | NS | PHT, PB | NS | Diagnosis of JAE. |
| | Agathonikou et al., 1998 [15] |
Patients 1–17 had defined IGE syndromes; moreover, patients 9, 10, 16, and 17 had presented only one AS episode. |
| | Baykan et al., 2002 [21] |
All 8 patients had recurrent AS but all of them were diagnosed with defined IGE syndromes. |
|
Nguyen Michel et al., 2011 [22]
(patient 5) | F | 71 | A, GTCS | NS | NS | LTG, LEV | ? | Diagnosis of CAE. |
|
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