Bridging the Gap between Evidence and Practice for Adults with Medically Refractory Temporal Lobe Epilepsy: Is a Change in Funding Policy Needed to Stimulate a Shift in Practice?

Table 2

Specific components of health economic evaluation conducted in selected studies.

First author	Type of economic evaluation	Outcome measure	Perspective	Modeling	Time horizon (years)	Discounting (rates in %)
Wiebe [18]	Intent-to-treat, CEA	Seizure freedom rate overall	Provider	Decision analysis modeling	Lifetime (35 years)	5
King [19]	Intent-to-treat, CUA	QALY	Societal	Markov state transition model	Lifetime	5
Langfitt [20]	CUA	QALY	Provider	Decision analysis modeling	Lifetime	5
Picot [23]	CEA alongside clinical study (280 patients total)	Seizure-freedom rate at 1 year	Societal	Monte Carlo simulation based on Markov transition model	Lifetime	3

Although referred to as a CEA, this was technically a CUA.