Table of Contents
Epilepsy Research and Treatment
Volume 2016 (2016), Article ID 9709056, 5 pages
http://dx.doi.org/10.1155/2016/9709056
Research Article

Neuromodulation Therapy with Vagus Nerve Stimulation for Intractable Epilepsy: A 2-Year Efficacy Analysis Study in Patients under 12 Years of Age

1Comprehensive Epilepsy Program, Southern California Permanente Medical Group, CA, USA
2Department of Neurology, Kaiser Permanente Medical Center, Suite No. 208, 3460 E. La Palma Avenue, Anaheim, CA 92806, USA

Received 28 October 2015; Revised 13 January 2016; Accepted 13 January 2016

Academic Editor: József Janszky

Copyright © 2016 Suresh Gurbani et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. Cyberonics, VNS Therapy Products Manuals and Safety Alerts: Part1—Introduction—Indications, Warnings and Precautions, Cyberonics, Houston, Tex, USA, 2012.
  2. M. C. Salinsky, B. M. Uthman, R. K. Ristanovic, J. F. Wernicke, and W. B. Tarver, “Vagus nerve stimulation for the treatment of medically intractable seizures: results of a 1-year open-extension trial,” Archives of Neurology, vol. 53, no. 11, pp. 1176–1180, 1996. View at Publisher · View at Google Scholar
  3. G. W. Hornig, J. V. Murphy, G. Schallert, and C. Tilton, “Left vagus nerve stimulation in children with refractory epilepsy: an update,” Southern Medical Journal, vol. 90, no. 5, pp. 484–488, 1997. View at Publisher · View at Google Scholar · View at Scopus
  4. J. V. Murphy, G. Hornig, and G. Schallert, “Left vagal nerve stimulation in children with refractory epilepsy: preliminary observations,” Archives of Neurology, vol. 52, no. 9, pp. 886–889, 1995. View at Publisher · View at Google Scholar · View at Scopus
  5. E. Ben-Menachem, R. Mañon-Espaillat, R. Ristanovic et al., “Vagus nerve stimulation for treatment of partial seizures: 1. A controlled study of effect on seizures. First International Vagus Nerve Stimulation Study Group,” Epilepsia, vol. 35, no. 3, pp. 616–626, 1994. View at Google Scholar
  6. C. M. DeGiorgio, S. C. Schachter, A. Handforth et al., “Prospective long-term study of vagus nerve stimulation for the treatment of refractory seizures,” Epilepsia, vol. 41, no. 9, pp. 1195–1200, 2000. View at Publisher · View at Google Scholar · View at Scopus
  7. M. Frost, J. Gates, S. L. Helmers et al., “Vagus nerve stimulation in children with refractory seizures associated with Lennox-Gastaut syndrome,” Epilepsia, vol. 42, no. 9, pp. 1148–1152, 2001. View at Publisher · View at Google Scholar · View at Scopus
  8. S. Chayasirisobhon, W. V. Chayasirisobhon, S. Koulouris, and S. Gurbani, “Vagus nerve stimulation in drug-resistant epilepsy,” Acta Neurologica Taiwanica, vol. 12, pp. 123–129, 2003. View at Google Scholar
  9. D. R. Labar, “Antiepileptic drug use during the first 12 months of vagus nerve stimulation therapy: a registry study,” Neurology, vol. 59, no. 6, supplement 4, pp. S38–S43, 2002. View at Publisher · View at Google Scholar · View at Scopus
  10. A. P. Amar, C. M. DeGiorgio, W. B. Tarver, and M. L. Apuzzo, “Long-term multicenter experience with vagus nerve stimulation for intractable partial seizures: results of the XE5 trial,” Stereotactic and Functional Neurosurgery, vol. 73, no. 1–4, pp. 104–108, 1999. View at Google Scholar
  11. E. Ben-Menachem, K. Hellström, C. Waldton, and L. E. Augustinsson, “Evaluation of refractory epilepsy treated with vagus nerve stimulation for up to 5 years,” Neurology, vol. 52, no. 6, pp. 1265–1267, 1999. View at Publisher · View at Google Scholar · View at Scopus
  12. J. Scherrmann, C. Hoppe, T. Kral, J. Schramm, and C. E. Elger, “Vagus nerve stimulation: clinical experience in a large patient series,” Journal of Clinical Neurophysiology, vol. 18, no. 5, pp. 408–414, 2001. View at Publisher · View at Google Scholar · View at Scopus
  13. J. V. Murphy, R. Torkelson, I. Dowler, S. Simon, and S. Hudson, “Vagal nerve stimulation in refractory epilepsy: the first 100 patients receiving vagal nerve stimulation at a pediatric epilepsy center,” Archives of Pediatrics and Adolescent Medicine, vol. 157, no. 6, pp. 560–564, 2003. View at Publisher · View at Google Scholar · View at Scopus
  14. B. M. Uthman, A. M. Reichl, J. C. Dean et al., “Effectiveness of vagus nerve stimulation in epilepsy patients: a 12-year observation,” Neurology, vol. 63, no. 6, pp. 1124–1126, 2004. View at Publisher · View at Google Scholar · View at Scopus
  15. K. Vonck, V. Thadani, K. Gilbert et al., “Vagus nerve stimulation for refractory epilepsy: a transatlantic experience,” Journal of Clinical Neurophysiology, vol. 21, no. 4, pp. 283–289, 2004. View at Publisher · View at Google Scholar · View at Scopus
  16. D. Labar, “Vagus nerve stimulation for 1 year in 269 patients on unchanged antiepileptic drugs,” Seizure, vol. 13, no. 6, pp. 392–398, 2004. View at Publisher · View at Google Scholar · View at Scopus
  17. A. V. Alexopoulos, P. Kotagal, T. Loddenkemper, J. Hammel, and W. E. Bingaman, “Long-term results with vagus nerve stimulation in children with pharmacoresistant epilepsy,” Seizure, vol. 15, no. 7, pp. 491–503, 2006. View at Publisher · View at Google Scholar · View at Scopus
  18. M. Benifla, J. T. Rutka, W. Logan, and E. J. Donner, “Vagal nerve stimulation for refractory epilepsy in children: indications and experience at the Hospital for Sick Children,” Child's Nervous System, vol. 22, no. 8, pp. 1018–1026, 2006. View at Publisher · View at Google Scholar · View at Scopus
  19. V. De Herdt, P. Boon, B. Ceulemans et al., “Vagus nerve stimulation for refractory epilepsy: a Belgian multicenter study,” European Journal of Paediatric Neurology, vol. 11, no. 5, pp. 261–269, 2007. View at Publisher · View at Google Scholar · View at Scopus
  20. A. P. Amar, M. L. Apuzzo, and C. Y. Liu, “Vagus nerve stimulation therapy after failed cranial surgery for intractable epilepsy: results from the vagus nerve stimulation therapy patient outcome registry,” Neurosurgery, vol. 62, supplement 2, pp. 506–513, 2008. View at Google Scholar
  21. R. E. Elliott, A. Morsi, S. P. Kalhorn et al., “Vagus nerve stimulation in 436 consecutive patients with treatment-resistant epilepsy: long-term outcomes and predictors of response,” Epilepsy and Behavior, vol. 20, no. 1, pp. 57–63, 2011. View at Publisher · View at Google Scholar · View at Scopus
  22. R. E. Elliott, A. Morsi, O. Tanweer et al., “Efficacy of vagus nerve stimulation over time: review of 65 consecutive patients with treatment-resistant epilepsy treated with VNS >10 years,” Epilepsy & Behavior, vol. 20, no. 3, pp. 478–483, 2011. View at Publisher · View at Google Scholar · View at Scopus
  23. N. Zamponi, C. Petrelli, C. Passamonti, R. Moavero, and P. Curatolo, “Vagus nerve stimulation for refractory epilepsy in tuberous sclerosis,” Pediatric Neurology, vol. 43, no. 1, pp. 29–34, 2010. View at Publisher · View at Google Scholar · View at Scopus
  24. T. Hallböök, J. Lundgren, K. Stjernqvist, G. Blennow, L.-G. Strömblad, and I. Rosén, “Vagus nerve stimulation in 15 children with therapy resistant epilepsy; its impact on cognition, quality of life, behaviour and mood,” Seizure, vol. 14, no. 7, pp. 504–513, 2005. View at Publisher · View at Google Scholar · View at Scopus
  25. H. C. Kang, Y. S. Hwang, D. S. Kim, and H. D. Kim, “Vagus nerve stimulation in pediatric intractable epilepsy: a Korean bicentric study,” in Advances in Functional and Reparative Neurosurgery, vol. 99 of Acta Neurochirurgica Supplementum, pp. 93–96, Springer, Vienna, Austria, 2006. View at Publisher · View at Google Scholar
  26. E. Rossignol, A. Lortie, T. Thomas et al., “Vagus nerve stimulation in pediatric epileptic syndromes,” Seizure, vol. 18, no. 1, pp. 34–37, 2009. View at Publisher · View at Google Scholar · View at Scopus
  27. A. Shahwan, C. Bailey, W. Maxiner, and A. S. Harvey, “Vagus nerve stimulation for refractory epilepsy in children: more to VNS than seizure frequency reduction,” Epilepsia, vol. 50, no. 5, pp. 1220–1228, 2009. View at Publisher · View at Google Scholar · View at Scopus
  28. N. Zamponi, C. Passamonti, E. Cesaroni, R. Trignani, and F. Rychlicki, “Effectiveness of vagal nerve stimulation (VNS) in patients with drop-attacks and different epileptic syndromes,” Seizure, vol. 20, no. 6, pp. 468–474, 2011. View at Publisher · View at Google Scholar · View at Scopus
  29. E. M. S. Sherman, M. B. Connolly, D. J. Slick, K. L. Eyrl, P. Steinbok, and K. Farrell, “Quality of life and seizure outcome after vagus nerve stimulation in children with intractable epilepsy,” Journal of Child Neurology, vol. 23, no. 9, pp. 991–998, 2008. View at Publisher · View at Google Scholar · View at Scopus
  30. G. Colicchio, D. Policicchio, G. Barbati et al., “Vagal nerve stimulation for drug-resistant epilepsies in different age, aetiology and duration,” Child's Nervous System, vol. 26, no. 6, pp. 811–819, 2010. View at Publisher · View at Google Scholar · View at Scopus
  31. B. Majkowska-Zwolińska, P. Zwoliński, M. Roszkowski, and K. Drabik, “Long-term results of vagus nerve stimulation in children and adolescents with drug-resistant epilepsy,” Child's Nervous System, vol. 28, no. 4, pp. 621–628, 2012. View at Publisher · View at Google Scholar · View at Scopus
  32. M. Wheeler, V. De Herdt, K. Vonck et al., “Efficacy of vagus nerve stimulation for refractory epilepsy among patient subgroups: a re-analysis using the Engel classification,” Seizure, vol. 20, no. 4, pp. 331–335, 2011. View at Publisher · View at Google Scholar · View at Scopus
  33. R. E. Elliott, S. D. Rodgers, L. Bassani et al., “Vagus nerve stimulation for children with treatment-resistant epilepsy: a consecutive series of 141 cases,” Journal of Neurosurgery: Pediatrics, vol. 7, no. 5, pp. 491–500, 2011. View at Publisher · View at Google Scholar · View at Scopus
  34. E. A. Pastrana, S. Estronza, and I. J. Sosa, “Vagus nerve stimulation for intractable seizures in children: the university of Puerto Rico experience,” Puerto Rico Health Sciences Journal, vol. 30, no. 3, pp. 128–131, 2011. View at Google Scholar · View at Scopus
  35. D. Parain, M. J. Penniello, P. Berquen, T. Delangre, C. Billard, and J. V. Murphy, “Vagal nerve stimulation in tuberous sclerosis complex patients,” Pediatric Neurology, vol. 25, no. 3, pp. 213–216, 2001. View at Publisher · View at Google Scholar · View at Scopus
  36. N. Zamponi, C. Passamonti, S. Cappanera, and C. Petrelli, “Clinical course of young patients with Dravet syndrome after vagal nerve stimulation,” European Journal of Paediatric Neurology, vol. 15, no. 1, pp. 8–14, 2011. View at Publisher · View at Google Scholar · View at Scopus
  37. D. R. Labar, “Antiepileptic drug use during the first 12 months of vagus nerve stimulation therapy: a registration study,” Neurology, vol. 59, pp. 538–543, 2002. View at Google Scholar
  38. E. García-Navarrete, C. V. Torres, I. Gallego, M. Navas, J. Pastor, and R. G. Sola, “Long-term results of vagal nerve stimulation for adults with medication-resistant epilepsy who have been on unchanged antiepileptic medication,” Seizure, vol. 22, no. 1, pp. 9–13, 2013. View at Publisher · View at Google Scholar · View at Scopus
  39. S. Chayasirisobhon, L. Cahan, S. H. Choi et al., “Efficacy of neuromodulation therapy with vagus nerve stimulator in patients with drug-resistant epilepsy on unchanged antiepileptic medication regimen for 24 months following the implant,” Journal of Neurology & Neurophysiology, vol. 6, pp. 1–4, 2015. View at Google Scholar
  40. T. R. Henry, “Anatomical, experimental, and mechanistic investigations,” in Vagus Nerve Stimulation, S. C. Schachter and D. Schmidt, Eds., pp. 1–29, Martin Dunitz, London, UK, 2001. View at Google Scholar
  41. S. G. Gurbani, M. Mittal, N. Gurbani, S. Koulouris, S. Choi, and S. Chayasirisobhon, “Efficacy of rapid cycling of vagus nerve stimulation in pharmaco-resistant epilepsy,” Neurology Asia, vol. 9, supplement 1, p. 131, 2004. View at Google Scholar