Spatial Organization and Dynamics of Transcription Elongation and Pre-mRNA Processing in Live Cells

<table>Model of the basic structure and function of RNAPII transcription factories. (a) A “gene-loop” is recruited upon activation to the transcription factory, which contains immobilized subunits of RNAPII. (b) The gene-loop is then “reeled” onto RNAPII for transcriptional elongation. (c) Upon termination, the anchoring of the locus allows for subsequent rounds of transcription. Adapted, with permission, from The Journal of Cell Science [<a href="/journals/gri/2011/626081/#B21">47</a>].</table>

Genetics Research International

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Figure 1

Figure 1: Spatial Organization and Dynamics of Transcription Elongation and Pre-mRNA Processing in Live Cells 