Review Article

How Can Satellite DNA Divergence Cause Reproductive Isolation? Let Us Count the Chromosomal Ways

Figure 2

Disruption of mitotic chromosome segregation in hybrid embryos caused by satellite chromatin defects. Chromatid pairs line up at the metaphase plate for segregation at anaphase (left of arrow). The top chromatids fail to segregate due to defective chromatin structure of the red satellite block (right of arrow). This phenotype is analogous to that involving the 359-bp satellite block in D. melanogaster/D. simulans hybrid embryos [1] and results from an incompatibility between a D. melanogaster-specific satellite and a putative chromatin-related factor in the D. simulans egg cytoplasm.
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