Genetics Research International / 2012 / Article / Fig 3

Review Article

Finding a Balance: How Diverse Dosage Compensation Strategies Modify Histone H4 to Regulate Transcription

Figure 3

A model of transcriptional regulation by H4K16ac. H4K16ac recruits the transcription elongation factor P-TEFb through the transcriptional coactivator BRD4. P-TEFb phosphorylates RNA Pol II, signaling the transition to productive elongation.

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