Finding a Balance: How Diverse Dosage Compensation Strategies Modify Histone H4 to Regulate Transcription

<table>A model of transcriptional regulation by H4K16ac. H4K16ac recruits the transcription elongation factor P-TEFb through the transcriptional coactivator BRD4. P-TEFb phosphorylates RNA Pol II, signaling the transition to productive elongation.</table>

Genetics Research International

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Figure 3

Figure 3: Finding a Balance: How Diverse Dosage Compensation Strategies Modify Histone H4 to Regulate Transcription 