Research Article
Power Estimation for Gene-Longevity Association Analysis Using Concordant Twins
Table 4
Power estimates for additive effects using longevity concordant DZ twins.
| Relative risk | 90+ | 95+ | 100 | 200 | 300 | 500 | 800 | 1500 | 100 | 200 | 300 | 500 | 800 | 1500 |
| MAF = 0.05 | | | | | | | | | | | | | 0.5 | 0.73 | 0.94 | 0.98 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.7 | 0.30 | 0.53 | 0.71 | 0.87 | 0.97 | 1.00 | 0.74 | 0.95 | 0.99 | 1.00 | 1.00 | 1.00 | 0.8 | 0.16 | 0.23 | 0.34 | 0.51 | 0.72 | 0.92 | 0.34 | 0.56 | 0.73 | 0.93 | 0.99 | 1.00 | 0.85 | 0.10 | 0.16 | 0.17 | 0.31 | 0.44 | 0.69 | 0.20 | 0.34 | 0.47 | 0.70 | 0.89 | 0.99 | 0.9 | 0.07 | 0.08 | 0.12 | 0.14 | 0.24 | 0.37 | 0.12 | 0.19 | 0.25 | 0.37 | 0.50 | 0.77 | 0.95 | 0.06 | 0.05 | 0.06 | 0.08 | 0.09 | 0.11 | 0.08 | 0.08 | 0.08 | 0.11 | 0.14 | 0.24 | MAF = 0.1 | | | | | | | | | | | | | 0.5 | 0.92 | 0.99 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.7 | 0.50 | 0.74 | 0.90 | 0.99 | 1.00 | 1.00 | 0.93 | 0.99 | 1.00 | 1.00 | 1.00 | 1.00 | 0.8 | 0.25 | 0.44 | 0.54 | 0.76 | 0.92 | 0.99 | 0.57 | 0.83 | 0.95 | 1.00 | 1.00 | 1.00 | 0.85 | 0.15 | 0.24 | 0.32 | 0.48 | 0.68 | 0.90 | 0.32 | 0.56 | 0.74 | 0.92 | 0.99 | 1.00 | 0.9 | 0.09 | 0.13 | 0.17 | 0.26 | 0.35 | 0.64 | 0.16 | 0.28 | 0.36 | 0.55 | 0.75 | 0.96 | 0.95 | 0.06 | 0.06 | 0.07 | 0.09 | 0.12 | 0.19 | 0.06 | 0.11 | 0.13 | 0.16 | 0.26 | 0.43 | MAF = 0.2 | | | | | | | | | | | | | 0.5 | 0.97 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.7 | 0.68 | 0.93 | 0.99 | 1.00 | 1.00 | 1.00 | 0.99 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.8 | 0.36 | 0.63 | 0.79 | 0.94 | 0.99 | 1.00 | 0.78 | 0.98 | 1.00 | 1.00 | 1.00 | 1.00 | 0.85 | 0.24 | 0.35 | 0.53 | 0.75 | 0.92 | 1.00 | 0.51 | 0.81 | 0.94 | 0.99 | 1.00 | 1.00 | 0.9 | 0.12 | 0.21 | 0.29 | 0.39 | 0.59 | 0.84 | 0.23 | 0.45 | 0.61 | 0.80 | 0.94 | 1.00 | 0.95 | 0.06 | 0.08 | 0.12 | 0.13 | 0.19 | 0.31 | 0.09 | 0.14 | 0.17 | 0.25 | 0.44 | 0.68 | MAF = 0.5 | | | | | | | | | | | | | 0.5 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.7 | 0.84 | 0.98 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.8 | 0.48 | 0.79 | 0.91 | 0.99 | 1.00 | 1.00 | 0.88 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.85 | 0.30 | 0.55 | 0.71 | 0.88 | 0.98 | 1.00 | 0.67 | 0.90 | 0.98 | 1.00 | 1.00 | 1.00 | 0.9 | 0.16 | 0.25 | 0.38 | 0.57 | 0.72 | 0.95 | 0.33 | 0.56 | 0.74 | 0.92 | 0.99 | 1.00 | 0.95 | 0.08 | 0.09 | 0.12 | 0.18 | 0.25 | 0.41 | 0.12 | 0.18 | 0.26 | 0.40 | 0.58 | 0.83 |
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Power estimates over the lines are acceptable.
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