Modulation at Age of Onset in Tunisian Huntington Disease Patients: Implication of New Modifier Genes

Table 2

Pearson correlation coefficient between studied polymorphisms and age at onset of HD in our population.

Gene (polymorphism)	Pearson correlation coefficient r	value
IT15 (expanded CAG)	−0.863	0.000*
IT15 (unexpanded CAG)	−0.383	0.176
DRPLA (CAG)	−0.225	0.440
DMPK (CTG)	0.295	0.306
ATXN1 (CAG)	−0.290	0.315
TBP (CAG)	−0.299	0.299
JPH3 (CTG)	−0.547	0.043*
TCERG1 (Gln-Ala)	−0.151	0.606
GRIN2A (rs1969060)	0.287	0.320
GRIN2B (rs890)	−0.129	0.661

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