An Introspective Update on the Influence of miRNAs in Breast Carcinoma and Neuroblastoma Chemoresistance

Table 2

miRNAs found to be associated with breast cancer and their respective target genes.

miRNA	Dysregulated expression	Target genes	References
miR-10a	Upregulated	Hox genes	[152, 153]
miR-21	Upregulated	PTEN, PDCD4	[154, 155]
miR-29a	Upregulated	PTEN	[155, 156]
miR-125b	Upregulated	E2F3	[155, 157]
miR-203	Upregulated	SOC3	[158]
miR-210	Upregulated	Efna3	[159]
miR-222	Upregulated	PTEN	[155, 157]
miR-30c	Downregulated	TWF I	[160]
miR-31	Downregulated	PKC epsilon	[161]
miR-34a	Downregulated	NOTCHI	[162]
miR-93	Downregulated	TGFβR2	[101, 155]
miR-128	Downregulated	BMII, ABCC5	[163]
miR-137	Downregulated	Pgp indirectly	[164]
miR-205	Downregulated	HMGB3	[119, 155]
miR-200a and 200b	Downregulated	ZEB 1/2	[155, 165]
miR-200c	Downregulated	ZEB I, CDH I, PTEN	[155, 166, 167]
miR-298	Downregulated	MDR (P-gp)	[168]
miR-487a	Downregulated	ABCG2 (BRCP)	[169]

PDCD4: programmed cell death 4, E2F3: E2F transcription factor 3, SOC3: suppressor of cytokine signalling 3, Efna3: ephrin A3, TWF I: twinfilin actin-binding protein I, PKC: protein kinase C, TGFβR2: transforming growth factor-β receptor II, ABCC5: ATP-binding cassette, Subfamily C Member 5, HMGB3: high mobility group box 3, ZEB: zinc finger E-box, CDH: cadherin, and ABCG2: ATP-binding cassette, Subfamily G Member 2.