Research Article
Leveraging Comparative Genomics to Identify and Functionally Characterize Genes Associated with Sperm Phenotypes in Python bivittatus (Burmese Python)
Table 1
Python orthologs of genes previously associated with sperm function and/or traits along with literature references.
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Python orthologs of genes previously associated with sperm function and/or traits along with literature references. Among a set of 21 P. regius gene sequences available within the NCBI database, 13 were implicated in sperm function and/or traits based on previous publications in other species. The table contains the P. regius NCBI identifiers and corresponding orthologous P. bivittatus gene identifiers (for genes in which the ortholog was identified). For each orthologous pair, the protein percent identity and -value obtained from the BLASTP analysis of the sequences are provided. Additionally, each P. regius gene identified has a reference implicating the gene in sperm related biology in another species. Together these genes represent evidence that P. bivittatus and P. regius exhibit high sequence identity among these genes. Specifically, 4 out of the 12 identified ortholog pairs have identity of 97% or greater (epididymal secretory protein E1, Kallikrein, Cystatin F, and cathepsin D), while just two ortholog pairs have percent identity below 90% (alpha enolase having 88% and mitochondrial NADH dehydrogenase subunit 4 with 89%). |