Unique AGG Interruption in the CGG Repeats of the FMR1 Gene Exclusively Found in Asians Linked to a Specific SNP Haplotype

Table 3

SNP haplotypes frequencies in different CGG repeat groups.

Haplotype	Frequencies of the CGG groups (number)
	19–28 CGG; (18)	29 CGG; (55)	30 CGG; (37)	31–35 CGG; (19)	36 CGG; (32)	37–56 CGG; (15)	Total number; (176)
GCGGATAA; (Hap A)	0.278; (5)	0.745; (41)	0.027; (1)	0.263; (5)	0.156; (5)	0.467; (7)	0.364; (64)
GCCGTTAA; (Hap B)	0.167; (3)	0.055; (3)	0	0.053; (1)	0.844; (27)	0.333; (5)	0.222; (39)
TTCATCGC; (Hap C)	0.333; (6)	0.018; (1)	0.811; (30)	0.526; (10)	0	0.200; (3)	0.284; (50)
Rare haplotypes; (Hap D)	0.222; (4)	0.182; (10)	0.162; (6)	0.158; (3)	0	0	0.130; (23)

Comparison based on CGG repeats groups.
Common CGG repeat groups (29, 30, and 36; Fisher’s exact test; value < 0.001; statistical significance).
Uncommon CGG repeat groups (19–28, 31–35, and 37–56; Fisher’s exact test; value = 0.0955; no statistical significance).