Electronic Northern Analysis of Genes and Modeling of Gene Networks Underlying Bovine Milk Fat Production

Figure 2

Interaction network of the genes involved in milk fat biosynthesis and secretion. STRING v9.1 was used to derive the network among genes involved in milk fat synthesis and secretion. FASN appears to be the central component in milk fat synthesis. The entire network appears to operate under two different control systems: one under PPARG and another under the joint control of SREBF1 and SREBF2. Three genes (ASAHL/NAAA, LASS2, and UGCG) involved in sphingolipid synthesis did not interact with any other gene/gene product in the network.