Research Article
Lack of Association between Variant rs7916697 in ATOH7 and Primary Open Angle Glaucoma in a Saudi Cohort
Table 3
Analysis of genotype effect on demographic and clinical characteristics within PAOG group.
| | Characteristics | Genotypes | p valuea | G/G
(n= 69)
No. () | G/A
(n= 89)
No. () | A/A
(n= 28)
No. () |
| | DEMOGRAPHIC | | | | | | Age in years, mean (SD) | 62.2 (9.7) | 60.0 (11.0) | 60.4 (11.4) | 0.413∗ | | Male | 35 (50.7) | 50 (56.1) | 16 (57.1) | 0.750 | | Female | 34 (49.3) | 39 (43.8) | 12 (42.8) | - | | MEDICAL HISTORY | | | | | | Family history of glaucoma | 6 (8.7) | 7 (7.8) | 5 (17.8) | 0.278 | | Smoking | 5 (7.2) | 12 (13.5) | 3 (10.7) | 0.455 | | Diabetes mellitus | 22 (31.9) | 38 (42.7) | 15 (53.5) | 0.116 | | Hypertension | 24 (34.8) | 33(37.0) | 14 (50.0) | 0.360 | | Coronary artery disease | 1 (1.4) | 4 (4.5) | 1 (3.5) | 0.557 | | Hypercholesterolemia | 3 (4.3) | 7 (7.8) | 4 (14.3) | 0.240 | | GLAUCOMA INDICES | | | | | | Intraocular pressure in mmHg, mean (SD) | 22.5 (8.9) | 24.0 (9.7) | 22.6 (7.9) | 0.444∗∗ | | Cup/disc ratio | 0.84 (0.6) | 0.75 (0.2) | 0.82 (0.1) | 0.259∗∗ | | Number of anti-glaucoma medications | 1.7 (1.1) | 2.0 (1.0) | 1.9 (1.1) | 0.325∗∗ |
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Chi 2 test. ∗One-way ANOVA. ∗∗Kruskal-Wallis test. |
