Review Article

CRISPR/Cas9 System: A Bacterial Tailor for Genomic Engineering

Figure 7

Different formats for gene editing using CRISPR/Cas9 in cultured cells: CRISPR/Cas9 components are delivered in DNA, RNA, or RNP formats. Delivery as RGN-ribonucleoproteins (RNPs) improves efficiency and specificity and sidesteps other limitations associated with the use of plasmids.