Review Article
Evolution of Interferon-Based Therapy for Chronic Hepatitis C
Table 2
Factors associated with response to interferon-based therapy for hepatitis C.
| Baseline |
| Virological factors | Hepatitis C virus genotype | Hepatitis C viral loads | Quasispecies |
| Host factors | Bridging fibrosis/cirrhosis | Gender | Age | Ethnicity | Insulin resistance | Obesity | Hepatic steatosis | Host genetics: genetic variation in IL28B | Coinfection with HIV | Nonresponse to previous interferon-based therapy |
| On-treatment |
| Rapid virological response (RVR) at week 4 | Early virological response (EVR) at week 12 | Complete EVR (cEVR) versus Partial EVR (pEVR) | Medical adherence |
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