Tumor Necrosis Factor Receptor 1 Expression Is Upregulated in Dendritic Cells in Patients with Chronic HCV Who Respond to Therapy
Figure 2
Peak TNFR1 mRNA values were higher in responder patients than nonresponder patients. TNFR1 mRNA levels of genotype 1 patients PBMC’s were ascertained by real time PCR. Twelve responders, 25 NR/Rel and 12 responders, 24 NR/Rel were assessed for TNFR1 and TNFR2 mRNA levels, respectively (Panel A and B). Line indicates 2 SD above mean control levels. Levels did not vary between sample triplicates. Statistical differences were assessed by test.