Table of Contents
Hepatitis Research and Treatment
Volume 2010, Article ID 961359, 4 pages
http://dx.doi.org/10.1155/2010/961359
Review Article

Hepatitis C in Haematological Patients

Division of Haematology, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam, Hong Kong

Received 19 April 2010; Revised 8 July 2010; Accepted 6 August 2010

Academic Editor: Tatehiro Kagawa

Copyright © 2010 Y. Y. Hwang and R. H. S. Liang. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

There is no consensus guideline concerning the management of chronic hepatitis C patients during chemotherapy, and immunosuppression. However, there are some suggestions in literature that hepatitis C viral load increases during chemotherapy and there is a risk of rebound immunity against hepatitis C after discontinuation of immunosuppression with a consequent liver injury. A close monitoring of liver function of these patients is prudent during treatment of haematological malignancy. Antiviral treatment is deferred after the completion of chemotherapy and recovery of patients' immunity to minimize the toxicity of treatment. A combination of pegylated interferon and ribavirin is the standard therapy in hepatitis C infected haematological patients.