TP53 Mutations and HBX Status Analysis in Hepatocellular Carcinomas from Iran: Evidence for Lack of Association between HBV Genotype D and TP53 R249S Mutations

Figure 2

Neighbor-joining phylogenetic analysis using HBS gene of genotype D. The four subgenotypes D1 to D4 sequences were extracted from GenBank. The HCC R249S positive case from the case-control study from The Gambia is shown by an orange arrow and corresponds to subgenotype D1 (green circle). Made by the software MEGA5 [23].