TP53 Mutations and HBX Status Analysis in Hepatocellular Carcinomas from Iran: Evidence for Lack of Association between HBV Genotype D and TP53 R249S Mutations

Table 1

Characteristics and molecular status of 21 HCC cases from Iran.

Characteristics	No. (%)
Mean age (±SD)	56.4 (±19.3)
Sex
Women	1 (4.8)
Men	20 (95.2)
HBV status
Positive	6 (28.6)
Negative	9 (42.8)
N/A	6 (28.6)
Cirrhosis
Present	7 (33.3)
Absent	7 (33.3)
N/A	7 (33.3)
TP53 mutation (R249S)
Absent	21 (100.0)
Present	0 (0.0)
HBV Double mutation  (1762^T/1764^A)
Absent	21 (100.0)
Present	0 (0.0)
HBX status
Complete	8 (38.1)
3′-Truncated	12 (57.1)
Absent	1 (4.8)

N/A: Not available.