Hepatitis Research and Treatment / 2011 / Article / Tab 1

Research Article

Hepatitis B and Hepatitis C Infection Biomarkers and TP53 Mutations in Hepatocellular Carcinomas from Colombia

Table 1

Clinicopathological data of HCC cases diagnosed at four health reference institutions during the period 2000–2007 in Colombia.

Frequency (%)

Mean age63.5 years
Age range25–88 years
Gender female/male43.2%/56.8%
Edmondson and Steiner's grade
 G14.9%
 G239%
 G356.1%
Histological type
 Trabecular56.5%
 Solid21.7%
 Mixte13%
 Glandular4.4%
 Pseudo-glandular4.4%
Biomarkers
 HBV58.1% (25/43)
 HCV37% (10/27)
 Coinfection19.2% (5/26)
 AFB1-DNA adducts0% (0/31)
TP53 gene
  Exon 7 (249ser mutation)10.5% (4/38)
  Exon 5 (G12457T mutation)2.9% (1/34)
  Exon 8 (G13804A mutation)2.9% (1/34)

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