Mutations in TP53 and CTNNB1 in Relation to Hepatitis B and C Infections in Hepatocellular Carcinomas from Thailand

Figure 1

Immunostaining of HCC sections ((a)–(g) × 200, (h) × 400). Accumulation of p53 in HCC with R249S (a) and P278R (b). Accumulation of HBxAg in hepatocytes of nontumoral (NT) and tumoral (T) tissues of HCC with overt HBV infection (c,d) or occult HBV infection (e,f). Accumulation of HCV E2 protein in tumor section of overt HBV/HCV (g) or occult HBV/HCV (h) coinfected HCC.