Table of Contents
Hepatitis Research and Treatment
Volume 2012, Article ID 976434, 6 pages
http://dx.doi.org/10.1155/2012/976434
Research Article

Phylogenetic Analysis of Hepatitis E Virus in Northwest India

1Advanced Research Lab, SMS Medical College, Jaipur, Rajasthan 302004, India
2Gastroenterology Department, Fortis Escorts Hospital, Jawaharlal Nehru Marg, Malviya Nagar, Jaipur, Rajasthan 302017, India

Received 31 May 2012; Revised 15 September 2012; Accepted 19 September 2012

Academic Editor: Yoichi Hiasa

Copyright © 2012 Nidhi Subhash Chandra et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Genotyping and subtyping are important to understand epidemiology of the hepatitis E virus so as to improve control measures to prevent transmission of virus in the community. Hence, the aim of the current study was to identify the prevalent HEV genotypes in Rajasthan in acute sporadic hepatitis E cases with varying degree of liver failure. We studied hepatitis E virus (HEV) isolates from hospitalized patients in Rajasthan, western India. In a total of seventeen HEV sequences, six acute viral hepatitis, seven acute liver failure, and 4 acute- on-chronic cases were analyzed. Subtypes 1a and 1c of HEV are prevalent in Northwest India.