Evaluation of the Significance of Pretreatment Liver Biopsy and Baseline Mental Health Disorder Diagnosis on Hepatitis C Treatment Completion Rates at a Veterans Affairs Medical Center

Table 1

Baseline characteristics.

Variables	Cohort (𝑛=375)
Gender
Male, 𝑛 (%)	367 (98%)
Female, 𝑛 (%)	8 (2%)
Race/ethnicity
Black, 𝑛 (%)	192 (52%)
White, 𝑛 (%)	141 (38%)
Unknown, 𝑛 (%)	22 (6%)
Other, 𝑛 (%)	20 (5%)
Genotype
1 and 4, 𝑛 (%)	301 (80%)
2 and 3, 𝑛 (%)	58 (15%)
Not documented, 𝑛 (%)	12 (3%)
Mixed, 𝑛 (%)	4 (1%)
Age (years), median (range)	53 (27–77)
BMI (kg/m^2)	29.2 (18.7–59.5)
Obese (BMI 30 to 39.9), 𝑛 (%)	149 (40%)
Overweight (BMI 25 to 29.9), 𝑛 (%)	137 (37%)
Morbidly obese (BMI ≥ 40), 𝑛 (%)	15 (4%)
HCV VL RNA (IU/mL), median (range)	1,350,000 (344–25,400,000)
Diabetes diagnosis, 𝑛 (%)	97 (26%)
HIV diagnosis
No, 𝑛 (%)	253 (68%)
Not assessed or not documented, 𝑛 (%)	87 (23%)
Yes, 𝑛 (%)	35 (9%)
Course of therapy
1st, 𝑛 (%)	252 (67%)
2nd, 𝑛 (%)	92 (25%)
3rd or more, 𝑛 (%)	31 (8%)
Concomitant substance abuse, 𝑛 (%)	11 (3%)
Concomitant alcohol use, 𝑛 (%)	30 (8%)
Alb (g/dL), median (range)	4.2 (2.7–5.3)
Hgb (g/dL), median (range)	14.6 (9.8–18.2)
INR, median (range)	1.0 (0.86–1.78)
PLT (THO/uL), median (range)	197.5 (42–439)
SCr (mg/dL), median (range)	1.0 (0.6–3.5)
Tbili (mg/dL), median (range)	0.8 (0.1–2.9)
WBC (THO/uL), median (range)	6.2 (2.2–14.9)