Measuring the Response of Extrahepatic Symptoms and Quality of Life to Antiviral Treatment in Patients with Hepatitis C

Table 5

Variables associated with pretreatment CWP.

	CWP before treatment	No CWP before treatment	Statistical significance (P value)
No. of painful joints	5.19	1.67	>0.001
VAS pain rating (mean)	5.7/10	2.7/10	>0.001
VAS interference rating (mean)	5.0/10	2.1/10	>0.001
HQLQ domain
Physical functioning	66.8	79.7	0.025
Role physical	46.5	65.1	0.025
Body pain	38.5	68.6	>0.001
General health	40.6	54.6	0.002
Vitality	47.1	45.8	NS (0.553)
Social functioning	52.4	65.9	0.028
Role emotional	46.2	70.1	0.005
Mental health	57.2	65.5	0.035
Health distress	56.1	66.5	NS (0.182)
Positive well-being	74.8	65.7	0.023
Hepatitis-specific functional limitations	48.5	62.2	0.014
Hepatitis-specific distress	26.3	14.0	NS (0.064)