The first Japanese case of fibrolamellar carcinoma (FLC) of the liver is described. The 17-year-old
Japanese male affected died of the disease 25 months after palliative operation. The diagnosis of FLC had
not been confirmed before autopsy. Pre-operative diagnosis of FLC is important to surgeons. Acccording
to the literature, FLC is rare in Asia. The endemic discrepancy may suggest that the carcinogenic factors
are different from those of general hepatocellular carcinoma.