Table of Contents
HPB Surgery
Volume 1, Issue 2, Pages 97-100

Plasma Gamma Globulin Levels After Splenectomy and Spleen Salvage

Department of Surgery and Microbiology, Erciyes University, School of Medicine, Kayseri, Turkey

Received 16 March 1988; Accepted 8 June 1988

Copyright © 1989 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A series of plasma globulin studies was carried out on 108 patients who were operated on for splenic trauma during the last 3 years. The reasons for splenectomy or spleen salvage were; gunshot wounds in 22 patients (20.3%); stab injuries in 10 patients (9.2%) and blunt abdominal trauma in 76 patients (70.3%). Plasma gamma globulin determinations were made on the 8th postoperative day and at 3 months. In the splenectomy group; plasma gamma globulin determinations demonstrated a significant reduction in serum IgM levels (p < 0.001) but no significant changes in IgA and IgG levels (p > 0.05). No changes were detected in IgA, IgG and IgM levels in the spleen salvage group (p > 0.05).

We believe that the preservation of the traumatized spleen should be the prime aim of surgeons.