Table of Contents
HPB Surgery
Volume 5, Issue 2, Pages 95-102

Intrahepatic Cholangiocarcinoma: Clinical Aspects, Pathology and Treatment

Department of Surgery, Mayo Clinic, 200 First Street, SW, Rochester, MN 55905, USA

Received 7 January 1991; Accepted 25 March 1991

Copyright © 1992 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Intrahepatic cholangiocarcinoma (ICC) is the second most common primary tumor of the liver. To further define its clinicopathology and surgical management, we reviewed our experience. Clinical presentations of 32 patients with ICC was similar to that with hepatocellular carcinoma. Jaundice occurred in only 27 percent. ICC was unresectable due to advanced disease stage in 81 percent. Six patients had curative resections with two 5 year disease free survivors. Underlying liver disease was associated with ICC in 34 percent of patients.