Table of Contents
HPB Surgery
Volume 7, Issue 2, Pages 111-124
http://dx.doi.org/10.1155/1993/26569

Maxon is an Optimal Suture for Bile Duct Anastomoses in Pigs

1Departments of Surgery, Anaesthesia and Intensive Care, & Histopathology, Flinders University, Bedford Park, Adelaide 5042, Australia
2Dept Surgery, Flinders Medical Centre, Bedford Park, 5042, Australia

Received 7 March 1993; Accepted 7 March 1993

Copyright © 1993 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. Three commonly used sutures were tested in a pig model of bile duct anastomosis to assess their relative contributions to inflammation and scarring.

Methods. Thirty pigs were randomised to bile duct division and anastomosis with either polyglyconate (Maxon), polyglactin 910 (Vicryl) or polypropylene (Prolene). Half the animals were sacrificed at two weeks and the remainder at 23 weeks. Anastomoses were assessed by cholangiography, scanning electron microscopy and light microscopy.

Results. There was less short term histological reaction with the two monofilament materials, Prolene and Maxon, compared to the braided suture Vicryl. Maxon was associated with less long term inflammation than Prolene, was found to handle better, and has an advantage over Prolene by being absorbable.

Conclusion. Maxon is an optimal suture for bile duct anastomoses. Its long term absorption characteristics make it suitable for situations where bile duct healing may be delayed.