The Prognostic Significance of the Preoperative Full Blood Count after Resection of Colorectal Liver Metastases

Table 4

Multivariate survival analysis of prognostic covariates in resected CRLM (Cox proportional hazards). (NB hazards ratio for continuous data reflects increase in relative risk of event with each incremental increase in covariate value of 1 unit).

	Overall survival		Disease free survival
	Hazards ratio	𝑃	Hazards ratio	𝑃
	(95% CI)		(95% CI)
Dukes stage	1.115 (0.652–1.908)	.691	1.170 (0.693–1.973)	.557
Resection margin	4.008 (1.567–10.252)	.004	6.599 (2.432–17.903)	.002
Hepatic lymph nodes	2.709 (1.194–6.145)	.017	1.732 (0.736–4.076)	.208
Unilobar versus bilobar disease	1.452 (0.869–2.427)	.154	1.968 (1.211–3.200)	.006
Platelet count^∗ (×10^9/L)	1.004 (1.002–1.007)	.002	1.003 (1.000–1.005)	.076
Lymphocyte count^∗ (×10^9/L)	1.022 (0.731–1.429)	.898	1.183 (0.809–1.731)	.386
Neutrophil count^∗ (×10^9/L)	1.043 (1.027–1.058)	<.001	1.018 (0.995–1.041)	.118
INR^∗	20.331 (0.869–475.645)	.061	1.813 (0.084–39.233)	.609

^∗Factors included as continuous covariates for Cox regression.