Disturbances in the Glutathione/Ophthalmate Redox Buffer System in the Woodchuck Model of Hepatitis Virus-Induced Hepatocellular Carcinoma

<table>Concentration of ophthalmate (OA) in RBC samples from the WHV-induced HCC woodchuck model (<i>μ</i>M). The concentrations of OA were measured in RBC samples of healthy woodchucks (WHV−/HCC−), WHV-infected woodchucks (WHV+/HCC−), and WHV-induced HCC animals (WHV+/HCC+, before and 8 hours after tumor ablation). The level of OA was higher in WHV+/HCC+ when compared to WHV+/HCC− and WHV−/HCC−. OA level was also higher in WHV+/HCC− when compared with the WHV−/HCC−. Levels of OA were similar in the WHV+/HCC+ group before and after tumor ablation. <svg height="13.95" id="M36" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 69.150002 13.95" width="69.150002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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HPB Surgery

fig6

Figure 6

Figure 6: Disturbances in the Glutathione/Ophthalmate Redox Buffer System in the Woodchuck Model of Hepatitis Virus-Induced Hepatocellular Carcinoma 