Research Article

Minocycline Decreases Liver Injury after Hemorrhagic Shock and Resuscitation in Mice

Figure 4

Minocycline and tetracycline decrease caspase 3 activation after hemorrhage and resuscitation. H/R was performed, as described in Figure 1, and caspase 3 activity was assessed in liver homogenates after sham operation or resuscitation with vehicle, minocycline, or tetracycline. Activity is expressed as fold increase over sham-operated mice. * versus vehicle.
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