C-Jun N-Terminal Kinase 2 Promotes Liver Injury via the Mitochondrial Permeability Transition after Hemorrhage and Resuscitation
Figure 2
Decreased necrosis after hemorrhage and resuscitation in JNK2 deficient mice. At 6 h after resuscitation, necrosis was assessed by H&E in livers from sham-operated wildtype mice (a) and from wildtype- (b) and JNK2-deficient (c) mice after H/R. Bar is 50 μm. In (d), the percent area of necrosis is averaged from 5 livers per group. Necrosis was not present after sham operation of either wildtype- or JNK2 deficient mice and is not plotted. *.
