HPB Surgery

HPB Surgery / 2014 / Article / Tab 1

Research Article

The Interaction between Diabetes, Body Mass Index, Hepatic Steatosis, and Risk of Liver Resection: Insulin Dependent Diabetes Is the Greatest Risk for Major Complications

Table 1

Analysis of factors associated with hepatic steatosis (≥33%) in 439 patients undergoing liver resection.

Steatosis < 33% Steatosis ≥ 33% Univariate Multivariate
Median (range)Count (%)Median (range)Count (%) valueComparisonOdds ratio (95% CI) value

Age65 (21–90)65 (41–87)0.622
Gender
 Female168 (44.4)24 (39.3)0.544
 Male210 (55.6)37 (60.7)
Liver-directed chemotherapy
 Yes132 (34.9)20 (32.8)1.000
 No246 (65.1)41 (67.2)
Preexisting chronic liver disease
 Yes6 (1.6)3 (4.9)0.228*0.869
 No372 (98.4)58 (95.1)
Preoperative jaundice (≥50 micromoles/L)
 Yes5 (1.3)00.800
 No373 (98.7)61 (100)
Hypoalbuminaemia (<35 g/L)
 Yes15 (4.0)1 (1.6)0.602
 No360 (95.2)59 (96.7)
 Not recorded3 (0.8)1 (1.6)
Raised preoperative alkaline phosphatase
 Yes92 (24.3)5 (8.2)0.008* 0.15 (0.05–0.46)0.001**
 No283 (74.9)55 (90.2)
 Not recorded3 (0.8)1 (1.6)
Raised preoperative transaminase
 Yes61 (16.1)18 (29.5)0.021* 3.82 (1.85–7.89)<0.001**
 No308 (81.5)42 (68.9)
 Not recorded9 (2.4)1 (1.6)
Diabetic status
 Nondiabetic342 (90.5)45 (73.8)0.001* Diabetic versus nondiabetic 2.69 (1.18–6.13)0.018**
 Non-insulin dependent26 (6.9)11 (18.0)
 Insulin dependent10 (2.6)5 (8.2)Insulin dependent versus non-insulin dependent4.31 (1.09–16.98)0.037**
Body mass index (kg/m2)
 <25141 (37.3)6 (10)<0.001* <25 versus ≥25 2.97 (1.59–5.57)0.001**
 25–29.9153 (40.5)27 (45.0)
 ≥3081 (21.4)27 (45.0) 25–29.9 versus ≥300.144
 Not recorded3 (0.8)1 (1.6)

*Significant at the level of 0.25 for univariate analysis and included in multivariate analysis.
**Significant at the level of 0.05 for multivariate analysis.