Research Article

The Interaction between Diabetes, Body Mass Index, Hepatic Steatosis, and Risk of Liver Resection: Insulin Dependent Diabetes Is the Greatest Risk for Major Complications

Table 3

Postoperative complications, 90-day mortality, and diabetic status in 504 patients undergoing liver resection (patients may have had more than one complication).

All patients Nondiabetic Non-insulin dependent diabetes Insulin dependent diabetes value Nondiabetic versus non-insulin dependent diabetic value Nondiabetic versus insulin dependent diabetic
Count (%)Count (%)Count (%)Count (%)

Any major complication94 (18.7)78 (17.4)9 (21.9)7 (46.6)0.5210.010
90-day mortality (Grade V)
 Liver failure9 (1.8)5 (1.1)310.023*0.180
 Sepsis4 (0.8)3 (0.7)100.2961.000
 Malignancy4 (0.8)3 (0.7)011.0000.124
 Pulmonary embolus1 (0.2)1 (0.2)001.0001.000
 Anastomotic leak1 (0.2)1 (0.2)001.0001.000
 Peptic ulcer1 (0.2)1 (0.2)001.0001.000
 Strangulated hernia1 (0.2)1 (0.2)001.0001.000
 Peritonitis1 (0.2)1 (0.2)001.0001.000
 Heart failure1 (0.2)1 (0.2)001.0001.000
 Total23 (4.6)17 (3.8)420.0890.122
Grade IV complications
 Posthepatectomy liver failure (PHLF)34 (6.7)30 (6.7)400.5150.613
 Renal dysfunction31 (6.2)24 (5.4)430.2800.050
 Respiratory failure requiring intensive care2 (0.4)2 (0.4)001.0001.000
 Total67 (13.3)56 (12.5)830.2240.421
Grade III complications
 Bile leak
  Drain12 (2.4)11 (2.5)010.6110.330
  ERCP11 (2.2)10 (2.2)101.0001.000
 Relaparotomy/relaparoscopy
  Washout3 (0.6)1 (0.2)110.1610.064
  Adhesiolysis2 (0.4)2 (0.4)001.0001.000
  Defunction for anastomotic leak1 (0.2)0100.0841.000
  Small bowel leak1 (0.2)1 (0.2)001.0001.000
 Drainage
  Liver abscess1 (0.2)1 (0.2)001.0001.000
  Pleural effusion1 (0.2)0011.0000.032
  Pneumothorax1 (0.2)1 (0.2)001.0001.000
  Subphrenic collection2 (0.4)2 (0.4)001.0001.000
 Total35 (6.9)29 (6.5)330.7430.077