Prevalence of Steatosis Hepatis in the Eurotransplant Region: Impact on Graft Acceptance Rates
Table 1
Donor data overview.
Total
Allocated
Transplanted
Discarded
P value
N
2653
1561
527
565
Gender (m) (n, %)
1418 (53.5)
816 (52.3)
268 (51.0)
334 (59.3)
0.007
Age1
51.3 ± 20.6
49.0 ± 20.8
53.25 ± 18.2
56.0 ± 21.3
< 0.001
Cause of Death
< 0.001
Trauma (n, %)
464 (17.5)
309 (19.8)
84 (15.9)
71 (12.6)
Cerebrovascular (n, %)
1308 (49.3)
716 (45.9)
288 (54.6)
304 (53.8)
Anoxia (n, %)
379 (14.3)
219 (14.0)
74 (14.0)
86 (15.2)
Other (n, %)
502 (18.9)
317 (20.3)
81 (15.4)
104 (18.4)
BMI (kg/m2)1
25.5 ± 4.9
25.0 ± 4.3
25.6 ± 4.6
26.8 ± 6.3
< 0.001
ICU stay (days)2
3.0 (5)
3 (5)
3 (6)
3 (4)
0.25
AST (U/l)2
52.0 (76)
49.0 (71)
47.0 (78)
64.5 (102)
< 0.001
ALT (U/l)2
34.0 (60)
34.0 (57)
34.0 (59)
36 (70)
0.08
GGT (U/l)2
44.0 (93)
39.0 (78)
47.0 (100)
70.0 (161)
< 0.001
Bilirubin (µmol/l)2
8.7 (10)
8.2 (10)
9.2 (10)
12.0 (14)
< 0.001
INR2
1.18 (02.4)
1.16 (0.25)
1.19 (0.27)
1.2 (0.29)
< 0.001
Creatinine (µmol/l)2
70.7 (57.3)
68.0 (55.75)
73.2 (51.85)
79.8 (68.58)
< 0.001
CRP (mg/l)2
139.9 (162.65)
136.8 (164.75)
142.5 (152.4)
143.6 (175.23)
0.29
Na++ (mmol/l)2
148.0 (76.0)
148.0 (11)
147.0 (10)
148.0 (12)
0.15
CPR (n, %)
177 (11)
128 (8.2)
14 (2.7)
35 (6.2)
< 0.001
Steatosis Hepatis in sonography or pathology (n, %)
828 (32.1)
409 (27.0)
146 (28.3)
273 (49.7)
< 0.001
Steatosis Hepatis confirmed only in pathology (n, %)
665 (26.6)
334 (22.4)
114 (22.9)
217 (42.4)
< 0.001
is presented as mean ± standard deviation. is presented as median (interquartile range). Abbreviations: ALT: alanine-aminotransferase; AST: aspartate-aminotransferase; BMI: body mass index; CPR: cardiopulmonary resuscitation; CRP: C-reactive protein; GGT: gamma-glutamyl transferase; ICU: intensive care unit; INR: international normalized ratio; Na+: serum sodium.