Research Article

Prevalence of Steatosis Hepatis in the Eurotransplant Region: Impact on Graft Acceptance Rates

Table 1

Donor data overview.

TotalAllocatedTransplantedDiscardedP value

N26531561527565
Gender (m) (n, %)1418 (53.5)816 (52.3)268 (51.0)334 (59.3)0.007
Age151.3 ± 20.649.0 ± 20.853.25 ± 18.256.0 ± 21.3< 0.001
Cause of Death< 0.001
 Trauma (n, %)464 (17.5)309 (19.8)84 (15.9)71 (12.6)
 Cerebrovascular (n, %)1308 (49.3)716 (45.9)288 (54.6)304 (53.8)
 Anoxia (n, %)379 (14.3)219 (14.0)74 (14.0)86 (15.2)
 Other (n, %)502 (18.9)317 (20.3)81 (15.4)104 (18.4)
BMI (kg/m2)125.5 ± 4.925.0 ± 4.325.6 ± 4.626.8 ± 6.3< 0.001
ICU stay (days)23.0 (5)3 (5)3 (6)3 (4)0.25
AST (U/l)252.0 (76)49.0 (71)47.0 (78)64.5 (102)< 0.001
ALT (U/l)234.0 (60)34.0 (57)34.0 (59)36 (70)0.08
GGT (U/l)244.0 (93)39.0 (78)47.0 (100)70.0 (161)< 0.001
Bilirubin (µmol/l)28.7 (10)8.2 (10)9.2 (10)12.0 (14)< 0.001
INR21.18 (02.4)1.16 (0.25)1.19 (0.27)1.2 (0.29)< 0.001
Creatinine (µmol/l)270.7 (57.3)68.0 (55.75)73.2 (51.85)79.8 (68.58)< 0.001
CRP (mg/l)2139.9 (162.65)136.8 (164.75)142.5 (152.4)143.6 (175.23)0.29
Na++ (mmol/l)2148.0 (76.0)148.0 (11)147.0 (10)148.0 (12)0.15
CPR (n, %)177 (11)128 (8.2)14 (2.7)35 (6.2)< 0.001
Steatosis Hepatis in sonography or pathology 
(n, %)
828 (32.1)409 (27.0)146 (28.3)273 (49.7)< 0.001
Steatosis Hepatis confirmed only in pathology (n, %)665 (26.6)334 (22.4)114 (22.9)217 (42.4)< 0.001

is presented as mean ± standard deviation. is presented as median (interquartile range). Abbreviations: ALT: alanine-aminotransferase; AST: aspartate-aminotransferase; BMI: body mass index; CPR: cardiopulmonary resuscitation; CRP: C-reactive protein; GGT: gamma-glutamyl transferase; ICU: intensive care unit; INR: international normalized ratio; Na+: serum sodium.