Review Article
The Role of Normothermic Perfusion in Liver Transplantation (TRaNsIT Study): A Systematic Review of Preliminary Studies
Table 3
Characteristics during normothermic ex vivo liver perfusion of included studies.
| | Study | Perfusate | Peak AST (U/L) | Peak ALT (U/L) | Final lactate (mmol/L) | pH | Bile production (mL/hr) | Hepatic artery flow (mL/minutes) | Portal venous flow (mL/minutes) | Device failure | Major Technical Complication |
| | Ravikumar et al. [39] | Gelofusine + 3-unit donor cross-matched PRBC | NA | NA | NA | NA (7.2–7.4) | NA | NA | NA | 0 | 0 |
| | Selzner et al. [42] | Steen Solution + 3-unit PRBC | 1647 (227–9200) | 444 (152–1460) | 1.46 (0.56–1.74) | 7.26 (7.13–7.33) | 7.6 (2.4–15.1) | 300 (200–400) | 1250 (1200–1300) | 0 | 0 |
| | Bral et al. [43] | Gelofusine + 3-unit type “O” PRBC | NA | NA | NA | NA | 6.2 (1.9–32.2) | NA | NA | 0 | 1 (Single liver discarded due to portal vein twist) |
| | Liu et al. [44] | Plasma + matched PRBC | NA | NA | NA | NA | NA (1–13) | NA | NA | 0 | 0 |
| | Nasralla et al. [45] | Gelofusine + 3-unit donor cross-matched PRBC | NA | NA | NA | NA | NA | NA | NA | 1 (Single liver discarded due to the pinch valve miscalibration causing hepatic artery hypoperfusion)
| 2 |
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PRBC: packed red blood cells; AST: aspartate aminotransferase; ALT: alanine amino transferase; NA: not available.
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