Normothermic Ex Vivo Machine Perfusion for Liver Grafts Recovered from Donors after Circulatory Death: A Systematic Review and Meta-Analysis

Table 1

Summary of pig liver perfusion study results.

Perfusion studies	Perfusate	Preservation time (hr)	Simulated transplant phase (hr)	WIT (min)	N-NMP	N- SCS	AST (U/L) NMP	AST (U/L) SCS	ALT  (U/L) NMP	ALT (U/L) SCS	NMP total bile (ml)	SCS total bile (ml)	NMP HA flow (ml/min)	SCS HA flow  (ml/min)
Boehnert et al. 2013	Steen	4 SCS + 8 NMP vs. 12 SCS	12	60	6	6	__	__			__	__
Liu et al. 2014	Whole blood	10	24	60	5	5							ml/min/100 g liver	ml/min/100 g
Banan et al. 2015	Saline + whole blood	6	2	40	3	3					__	__
Nassar et al. 2015	Acellular solutions + whole blood	10	24	60	15	5							ml/min/100 g	57 ± 14 ml/min/100 g
Liu et al. 2016	Steen + RBC	10	24	60	5	5							__	__
Nassar et al. 2016	Whole blood	10	24	60	5	5							__	__
St Peter et al. 2002	Whole blood	24	24	60	4	4	259	3810			__	__	1400 ml/min	440 ml/min

  denotes values estimated from published figures where raw data are not available for analysis. __ denotes data not available for meta-analysis. AST/ALT values are taken at the end of the simulated transplant reperfusion phase. HA flows are ml/min unless units otherwise specified.