Estimation of the Age of the Kashubian-Specific Pathogenic NPHS2 Variant Responsible for Hereditary Steroid-Resistant Nephrotic Syndrome Points to Its Recent Local Origin

Table 2

Summary of analyzed SRNS families.

Patient	Genotype	Gender	Paternal alleles	Maternal alleles
1	c.1032delT/c.686G>A	f	c.1032delT	c.686G>A
2	c.1032delT/c.686G>A	m	c.1032delT/c.686G>A	c.686G>A
3	c.1032delT/c.686G>A	f	c.1032delT	c.686G>A
4	c.1032delT/c.1032delT	f	c.1032delT	c.1032delT
5	c.1032delT/c.686G>A	f	c.686G>A	c.1032delT
6	c.1032delT/c.686G>A	f	na	na
7	c.1032delT/c.686G>A	m	c.1032delT	c.686G>A
8	c.1032delT/c.686G>A	f	c.1032delT	c.686G>A

Parental alleles with the available haplotype data are indicated in bold. The c.686G>A allele not transferred to the affected child is underlined. An asterisk indicates the genotype from the consanguineous union, counted as a single allele. f: female; m: male.