Research Article

Inhibition of Quorum Sensing-Controlled Virulence Factors and Biofilm Formation in Pseudomonas aeruginosa by Culture Extract from Novel Bacterial Species of Paenibacillus Using a Rat Model of Chronic Lung Infection

Table 2

Microscopic lung pathology among experimental rats.

Experimental groups (number of rats)Microscopic lung pathology
Chronic inflammation
Number (%)
Score I
Number (%)
Score II
Number (%)
Score III
Number (%)
Score IV
Number (%)

Negative control (12) 012 (25%)000
Positive control (12) 12 (25%)002 (4.16%)10 (20.83%)
Comparative control (12) 6 (12.5%)1 (2.08%)5 (10.4%)4 (8.33%)2 (4.16%)
Extract treatment (12) 6 (12.5%)06 (12.5%)5 (10.4%)1 (2.08%)
Total (48)18 (37.5%)13 (27.08%)11 (22.91%)11 (22.91%)13 (27.08%)