Prenatal Curcumin Administration Reverses Behavioral and Neurochemical Effects and Decreases iNOS and COX-2 Expressions in Ischemic Rat Pups

Figure 3

Representative cresyl violet staining photomicrographs of CA1 and CA3 hippocampal areas (a), (b), (c) from ischemic pups (ISC) of untreated (ICUD) or curcumin treated dams (ICTD) at three postischemia times. Lower numbers of viable neurons are seen in ischemic pups from untreated dams, as related to those from curcumin (25 mg/kg) treated dams (ISC + C25), at the 1st, 7th, and 14th postischemia days. The arrows indicate dark or degenerated neurons. Scale bars represent 200 μm at the 1st day, 200 and 50 μm at the 7th day, and 200 μm at the 14th day after ischemia (magnification: ×100).

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