Table of Contents
International Journal of Brain Science
Volume 2014, Article ID 946039, 7 pages
Research Article

The Elusive Role of the Left Temporal Pole (BA38) in Language: A Preliminary Meta-Analytic Connectivity Study

1Department of Communication Sciences and Disorders, Florida International University, 11200 SW 8th Street, AHC3-431B, Miami, FL 33199, USA
2Department of Radiology/Research Institute, Miami Children’s Hospital, Miami, FL, USA
3Department of Psychology, Florida Atlantic University, Davie, FL, USA

Received 26 August 2014; Revised 4 October 2014; Accepted 7 October 2014; Published 21 October 2014

Academic Editor: João Quevedo

Copyright © 2014 Alfredo Ardila et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


It has been suggested that the left temporal pole (Brodmann area 38 (BA38)) participates in diverse language functions, including semantic processing, speech comprehension, and naming. Utilizing the activation likelihood estimation (ALE), a meta-analytic connectivity study was conducted to further our understanding on the role of BA38 in language. Departing from the BrainMap functional database, 11 papers corresponding to 12 paradigms including 201 participants were selected. Initially, was employed as the significance level, resulting in the presence of four different activation clusters. However, when the significance level was lowered to , sixteen activation clusters appeared, including classical language areas such as Broca’s and Wernicke’s areas. It was concluded that (1) this meta-analytic connectivity study suggests the presence of two major connection circuits involving BA38; one is related to language, while the other may be involved in visuospatial and integrative audiovisual functions. Furthermore, (2) BA38 also contributes to various brain networks supporting linguistic processes related not only to language comprehension but also to language production.