Efficacy of the Synbiotic Supplementation on the Metabolic Factors in Patients with Metabolic Syndrome: A Randomized, Triple-Blind, Placebo-Controlled Trial
Table 3
Anthropometric indices and blood pressure before and after the trial (mean ± SD).
Variables
Mean ± SD
value2
value3
Synbiotics (n = 52
Placebo (n = 56)
Weight (kg)
Baseline
84.28 ± 14.92
82.04 ± 14.24
0.503
At 12 wk
82.12 ± 14.29
79.43 ± 13.55
0.325
value1
<0.001
<0.001
0.420
BMI
Baseline
31.03 ± 4.91
31.14 ± 5.33
0.91
At 12 wk
30.67 ± 4.73
30.62 ± 5.29
0.84
value1
<0.001
<0.001
0.31
WC (cm)
Baseline
104.84 ± 9.74
104.60 ± 9.99
0.900
At 12 wk
99.49 ± 8.98
99.53 ± 10.38
0.981
value1
<0.001
<0.001
0.640
HC (cm)
Baseline
108.86 ± 9.90
109.28 ± 10.22
0.82
At 12 wk
104.50 ± 9.07
104.38 ± 9.06
0.94
value1
<0.001
<0.001
0.56
WHR
Baseline
0.93 ± 0.06
0.94 ± 0.06
0.78
At 12 wk
0.90 ± 0.06
0.91 ± 0.05
0.52
value1
<0.001
<0.001
0.58
SBP (mmHg)
Baseline
118.98 ± 12.94
120.85 ± 14.23
0.486
At 12 wk
114.19 ± 11.31
113.76 ± 10.30
0.841
P value1
0.039
<0.001
0.272
DBP (mmHg)
Baseline
81.22 ± 8.7
81.94 ± 9.45
0.686
At 12 wk
79.30 ± 8.85
78.29 ± 7.14
0.530
value1
0.147
0.014
0.480
LBM (kg)
Baseline
54.72 ± 11.30
52.82 ± 9.55
0.34
At 12 wk
55.10 ± 11.31
52.69 ± 9.16
0.23
value1
0.55
0.78
0.75
Body proteins (kg)
Baseline
10.52 ± 2.38
10.11 ± 2.00
0.33
At 12 wk
10.57 ± 2.34
10.16 ± 2.05
0.34
value1
0.04
0.03
0.98
Body fat (%)
Baseline
35.53 ± 5.76
35.94 ± 6.37
0.72
At 12 wk
33.81 ± 6.40
33.74 ± 7.26
0.95
value1
<0.001
<0.001
0.39
value1: significance of within-group alterations (paired t-test); value2: significance of between-group alterations (independent t-test); value3: treatment by analysis of covariance (adjusted baseline variable). WC: waist circumference; BMI: body mass index; HC: hip circumference; WHR: waist–hip ratio; LBM: loan body mass SBP: systolic blood pressure; DBP: diastolic blood pressure.
