Research Article

Effect of Glucocorticoid Administration in Intravenous Pulses on Selected Parameters of the Coagulation System

Table 2

Comparison of coagulation system parameters of the study and control groups before methylprednisolone administration.

VariableControl (n = 20)Study (n = 48)
Mean (SD)Mean (SD)

Factor VIII118.40 (32.35)118.73 (26.94)0.968
Factor IX110.50 (14.14)115.73 (14.67)0.178
Factor XI108.35 (12.08)109.56 (16.94)0.740
AT96.55 (10.61)103.44 (7.19)0.013
PC act.117.40 (20.77)119.42 (17.95)0.707
PS act.81.30 (14.92)82.42 (21.65)0.808
sTF139.32 (42.87)130.06 (39.15)0.421
APTT29.85 (3.66)29.13 (3.09)0.443

For sTF n = 19, due to the extremely high sTF values, significantly different from the rest of the measurements, in one patient of the study group, the result was not taken into account in the statistical analysis. APTT = activated partial thromboplastin time; AT = antithrombin; PC act. = protein C activity; PS act. = protein S activity; sTF = soluble tissue factor.