Research Article

Effect of Anemia on Readmission and Death in Octogenarian Patients with Lower Respiratory Tract Infections: A Retrospective Cohort Study

Table 1

Baseline characteristics of the study population.

CharacteristicsAnemia (n = 149)No anemia (n = 66) value

Age, mean (SD), y89.12 (4.9)87.86 (4.3)0.070
Male, no. (%)127 (85.2)39 (59.1)<0.001
Smoking, no. (%)5 (3.4)7 (10.6)0.070

Comorbidity, no. (%)
 Hypertension111 (74.5)53 (80.3)0.36
 Ischemic heart disease83 (55.7)29 (43.9)0.11
 Chronic heart failure (NYHA)
  Class I-II, no. (%)113 (75.8)52 (78.8)0.64
 Diabetes mellitus69 (46.3)31 (47)0.93
 Chronic kidney disease
  ≥3 stage53 (35.6)23 (34.8)0.92
 Liver injury17 (11.4)6 (9.1)0.61
 History of cancer24 (16.1)8 (12.1)0.45
 Dementia52 (34.9)10 (15.2)0.003

Medicine, no. (%)
 Erythropoietin25 (16.8)1 (1.5)0.002
 Oral iron34 (22.8)2 (3.0)<0.001
 Folic acid26 (17.4)1 (1.5)0.001
 Vitamin B1230 (20.1)6 (9.1)0.045
 Oral glucocorticoid11 (7.4)5 (7.6)1.00
 Inhaled glucocorticoid11 (7.4)6 (9.1)0.67
 Statin80 (53.7)39 (59.1)0.46
 Oral amino acid19 (13.0)4 (6.3)0.14

Laboratory test, mean (SD)
 Hemoglobin, mean (SD), g/L105.63 (12.88)132.32 (9.23)<0.001
 Total protein, mean (SD), g/L60.67 (7.97)63.46 (5.87)<0.001
 Albumin, mean (SD), g/L31.26 (3.60)35.12 (3.57)<0.001
 Sodium, mean (SD), mmol/L136.8 (10.95)139.7 (3.80)0.002
 Glucose, mean (SD), mmol/L6.18 (2.16)5.80 (1.68)0.65
 Total cholesterol, mean (SD), mmol/L3.46 (0.77)4.05 (0.90)<0.001
 Triglyceride, mean (SD), mmol/L0.93 (0.56)1.01 (0.52)0.013
 Low-density lipoprotein cholesterol, mean (SD), mmol/L1.91 (0.78)2.33 (0.75)<0.001
 High-density lipoprotein cholesterol, mean (SD), mmol/L1.02 (0.35)1.13 (0.35)0.031
 Glycosylated hemoglobin (HBA1c), mean (SD), %6.37 (0.97)6.48 (1.14)0.98

SD, standard deviation; NYHA, New York heart association.