International Journal of Clinical Practice

Research Article

Probiotic Foods Are Effective on Weight Loss, Biochemical Parameters, and Intestinal Microbiota in Wistar Albino Rats with Obese Microbiota

Table 6

The comparison of hematological parameters before and after dietary.


Hematological parameters	Pre-post	NDC^a (n = 7)	HFDC^b (n = 7)	Kefir + HFD^c (n = 7)	Tarhana + HFD^d (n = 7)	Kefir + Tarhana + HFD^e (n = 7)	p value

RBC (7.27–9.65 X miilion/mm³)	6th month	8.06 ± 1.12^a	5.72 ± 1.88^ba,b,a	6.90 ± 1.89^b	6.13 ± 1.57^b	5.44 ± 1.34^ea,b	0.00
	3rd month	8.23 ± 0.90^a	5.12 ± 0.95^ba,b	5.02 ± 0.79^ca,b	5.25 ± 0.98^da,b	4.61 ± 0.63^ea,b	0.00
	0th day	8.58 ± 1.42^a	8.53 ± 1.25^a	7.63 ± 1.14^a	8.35 ± 1.50^a	8.66 ± 1.06^a	0.59
	p value	0.72	0.00	0.02	0.02	0.00

HCT (39–53 %)	6th month	44.00 ± 0.81^a	30.85 ± 11.59^b	34.85 ± 9.90^b,a	32.71 ± 10.19^b,a	30.14 ± 7.60^ea,b	0.04
	3rd month	44.69 ± 0.73^a	24.31 ± 0.98^ba,b	26.77 ± 2.70^{ca, b}	27.93 ± 3.26^da,b	25.78 ± 3.04^ea,b	0.00
	0th day	44.27 ± 3.14^a	45.97 ± 1.96^a	45.17 ± 4.43^a	44.25 ± 3.52^a	47.80 ± 4.28^a	0.33
	p value	0.24	0.00	0.00	0.00	0.00

MCV (49-58 um³)	6th month	53.57 ± 6.34a	52.28 ± 4.43^b,a	50.85 ± 5.58^b,a	52.57 ± 4.92^a	55.14 ± 4.84^a	0.66
	3rd month	53.57 ± 0.78^a	51.42 ± 0.97^ba,b	51.42 ± 0.97^ca,b	51.71 ± 0.75^da,a	50.78 ± 0.56^ea,a	0.00
	0th day	53.28 ± 1.60^a	53.75 ± 1.29^a	54.56 ± 2.14^a	53.43 ± 1.58^a	52.98 ± 2.42^a	0.57
	p value	0.85	0.04	0.05	0.25	0.08

HGB (13.7–17.6 g/dl)	6th month	16.28 ± 0.75a	9.72 ± 3.57^ba,b	10.98 ± 3.78^ca,b	10.41 ± 3.44^da,a	10.22 ± 2.43^ea,c	0.00
	3rd month	16.49 ± 0.75a	7.25 ± 1.05^ba,b	7.37 ± 1.36^ca,b	7.81 ± 1.52^da,a	7.57 ± 1.41^ea,b	0.00
	0th day	15.91 ± 0.60a	15.63 ± 1.08^a	16.48 ± 0.48^a	16.69 ± 0.66^a	15.90 ± 0.63^a	0.05
	p value	0.44	0.00	0.00	0.25	0.00

MCH (17–20 pg)	6th month	16.85 ± 2.26^a	16.85 ± 2.91^{b, a}	16.00 ± 2.08^{b, a}	16.57 ± 2.14^{b, a}	19.14 ± 1.57^a	0.11
	3rd month	17.71 ± 0.75^a	15.42 ± 0.53^{ba, b}	15.71 ± 0.48^{ca, b}	15.42 ± 0.53^da,b	15.71 ± 0.75^ea,b	0.00
	0th day	18.26 ± 1.16^a	18.20 ± 0.76^a	18.22 ± 0.76^a	17.77 ± 0.30^a	18.54 ± 1.06^a	0.59
	p value	0.50	0.00	0.00	0.00	0.00

MCHC (33–38 g/dl)	6th month	36.28 ± 0.48^a	32.00 ± 3.26^ba,b	31.14 ± 1.57^ca,c	31.14 ± 1.51^da,b	33.85 ± 2.34^c	0.00
	3rd month	36.41 ± 0.56^a	28.00 ± 2.94^ba,b	27.00 ± 1.29^ca,b	28.71 ± 1.49^da,b	27.57 ± 2.29^ea,b	0.00
	0th day	36.82 ± 1.27^a	37.05 ± 1.18^a	36.62 ± 1.31^a	36.91 ± 1.10^a	37.34 ± 0.97^a	0.83
	p value	0.34	0.00	0.00	0.00	0.00

PLT (638–1117X bin/mm3)	6th month	643.85 ± 0.89a	142.42 ± 15.43^ba,b	138.85 ± 19.33^ca,b	147.14 ± 18.09^da,b	139.71 ± 17.00^ea,b	0.00
	3rd month	643.28 ± 0.48^a	133.57 ± 9.30^ba,b	134.28 ± 5.67^ca,b	129.08 ± 7.04^da,b	132.71 ± 9.39^ea,b	0.00
	0th day	643.02 ± 3.06^a	641.67 ± 3.51^a	640.30 ± 2.47^a	642.28 ± 2.6 9^a	644.00 ± 2.08^a	0.17
	p value	0.26	0.00	0.00	0.00	0.00

WBC (2.0–8.25X bin/mm3)	6th month	5.52 ± 0.17^a	0.58 ± 0.13^ba,b	0.68 ± 0.23^ca,b	0.68 ± 0.30^da,b	0.60 ± 0.23^ea,b	0.00
	3rd month	5.38 ± 0.18^a	0.35 ± 0.10^ba,b	0.39 ± 0.08^ca,b	0.36 ± 0.10^da,b	0.36 ± 0.09^ea,b	0.00
	0th day	5.34 ± 0.21^a	5.31 ± 0.23^a	5.46 ± 0.28 a	5.30 ± 0.29^a	5.29 ± 0.315^a	0.77
	p value	0.17	0.00	0.00	0.00	0.00

NDC, Normal Diet Control; HFDC, High fat diet control; Kefir + HFD, Kefir + High fat diet; Tarhana + HFD, Tarhana + High fat diet; Kefir + Tarhana + HFD, Kefir + Tarhana + High Fat Diet, a, b, c, d, e: Lettering represents groups. It states that there is a significant difference between the groups represented b y the letters in the double lettering. p values are for changes between groups (). Multiple group comparisons were performed using one-way ANOVA and Tukey’s HSD posthoc test. a, b, c: Lettering represents time points. The difference in averages was made by Bonferroni multiple comparisons. The differ ences with 95% confidence were marked with different notations. values are for changes within groups ().