Role of Oxidative Stress in Obese and Nonobese PCOS Patients

Table 2

Descriptive statistics and comparison results (results of biochemical parameters).

	Control group (n = 49)	Nonobese PCOS group (n = 45)	Obese PCOS group (n = 45)	value
Androstenedione (ng/ml)	1.77 ± 0.87^c	4.15 ± 1.55^b	4.89 ± 1.22^a	0.001
Total testosteron (ng/ml))	1.41 ± 0.68^c	4.10 ± 1.33^b	4.53 ± 1.31^a	0.001
Prolactin (ng/ml)	17.60 ± 3.31^a	19.9 ± 4.6^a	21.7 ± 6.6^a	0.560
DHEA-S (ug/dl)	155.8 ± 24.3^c	302.1 ± 65.2^b	335.3 ± 40.2^a	0.001
FSH (mu/ml	5.4 ± 1.80^a	4.6 ± 1.01^a	4.4 ± 1.41^a	0.218
LH (mu/ml)	4.63 ± 1.11^c	8.23 ± 2.08^b	7.55 ± 2.34^a	0.001
Insulin (U/ml)	4.05 ± 2.02^c	5.8 ± 3.77^b	10.64 ± 4.90^a	0.001
TSH (uIu/dl)	1.5 ± 0.81^a	1.72 ± 1.33^a	1.32 ± 0.61^a	0.765
SHBG (nmol/l)	135.2 ± 11.49^a	64.5 ± 14.33^b	45.6 ± 16.54^c	0.001
HDL (mg/dl)	53.50 ± 2.62^a	51.21 ± 4.71^b	39.23 ± 5.41^c	0.001
LDL (mg/dl)	82.6 ± 7.3^c	87.1 ± 4.6^b	126.1 ± 18.9^a	0.001
Triglyceride (mg/dl)	68.17 ± 12.2^c	84.80 ± 33.7^b	176.10 ± 21.38^a	0.001
Total cholesterol (mg/dl)	127.11 ± 10.1^c	158.28 ± 18.4^b	197.28 ± 22.23^a	0.001
FPG (mg/dl)	86.21 ± 8.81^c	94.10 ± 12.2^b	132.33 ± 18.2^a	0.001
MDA (umol/L)	0.104 ± 0.011^a	0.229 ± 0,055^b	0.273 ± 0.011^c	0.001
SOD (U/L)	142.410 ± 12.15^a	82.690 ± 9.87^b	66.320 ± 10.63^c	0.001
GPx (u/ml)	0.840 ± 0.086^a	0.074 ± 0.039^b	0,061 ± 0,040^c	0.001
CAT (u/ml)	390.256 ± 39.10^a	175.132 ± 58.68^b	144.100 ± 58.70^c	0.001
GSH (mg/dl)	0.167 ± 0.009^a	0.054 ± 0.017^b	0.035 ± 0.019^c	0.001

a: significantly different from the obese PCOS group and the nonobese PCOS group ( < 0.05). b: significantly different from the obese PCOS group and controls ( < 0.05). c: significantly different from the nonobese PCOS group and controls ( < 0.05). Values are expressed as mean ± SD. Statistical significance was defined as ( < 0.05). FPG: fasting plasma glucose. DHEA-S: dehydroepiandrosterone sulfate.