Research Article

Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children with Attention Deficit Hyperactivity Disorder

Table 4

Comparison of the mean difference of variables at the beginning and end of the study (end-beginning) between the two groups.

Variable (%)Placebo controlVitamin D value
BeforeAfterBeforeAfter

TAC (ng/ml)18.57 (2.12)17.69 (2.40)19.22 (2.54)14.90 (1.90)0.07
PON-1 (pg/ml)101.91 (12.83)101.80 (13.31)96.05 (13.37)94.65 (12.69)0.70
8-Isoprostane (pg/ml)218.27 (34.73)282.21 (49.98)194.24 (32.86)239.70 (41.50)0.75
Vitamin D3 (ng/ml)15.99 (1.88)15.99 (1.88)23.52 (1.75)33.44 (2.14)0.01

Univariate covariance analysis (ANCOVA) adjusted for the baseline vitamin D; mean ± standard error; TAC: total antioxidant capacity; PON-1: paraxonase-1; 8-isoprostane; vitamin D3.