A Novel Risk-Prediction Scoring System for Sepsis among Patients with Acute Pancreatitis: A Retrospective Analysis of a Large Clinical Database

Table 3

Predictive performances and validation of the nomogram.

Predictive model	AUC	value	NRI	value	IDI	value
Training cohort
Nomogram	0.730 (0.700–0.765)
BISAP	0.632 (0.595–0.673)	<0.001	0.548 (0.379–0.736)	<0.001	0.118 (0.096–0.141)	<0.001
SOFA	0.627 (0.583–0.681)	<0.001	0.549 (0.423–0.721)	<0.001	0.124 (0.101–0.147)	<0.001
qSOFA	0.524 (0.481–0.562)	<0.001	0.726 (0.597–0.854)	<0.001	0.163 (0.139–0.187)	<0.001
SIRS	0.613 (0.573–0.652)	<0.001	0.550 (0.393–0.741)	<0.001	0.128 (0.102–0.154)	<0.001
Validation cohort
Nomogram	0.732 (0.680–0.780)
BISAP	0.666 (0.609–0.723)	0.005	0.460 (0.165–0.751)	<0.001	0.092 (0.056–0.128)	<0.001
SOFA	0.677 (0.595–0.747)	<0.001	0.588 (0.375–0.863)	<0.001	0.133 (0.098–0.168)	<0.001
qSOFA	0.488 (0.421–0.549)	<0.001	0.718 (0.552–0.947)	<0.001	0.168 (0.131–0.204)	<0.001
SIRS	0.614 (0.552–0.673)	<0.001	0.592 (0.370–0.865)	<0.001	0.136 (0.097–0.175)	<0.001

Abbreviations: AUC, area under the receiver operating characteristic curve; NRI, net reclassification improvement; IDI, integrated discrimination improvement; BISAP, blood urea nitrogen, impaired mental status, systemic inflammatory response syndrome, age and pleural effusion; SOFA, Sequential Organ Failure Assessment; SIRS, systemic inflammatory response syndrome.